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Microtubules stabilize cell polarity by localizing rear signals

Microtubules are known to play an important role in cell polarity; however, the mechanism remains unclear. Using cells migrating persistently on micropatterned strips, we found that depolymerization of microtubules caused cells to change from persistent to oscillatory migration. Mathematical modelin...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Zhang, Jian, Guo, Wei-Hui, Wang, Yu-Li
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246331/
https://ncbi.nlm.nih.gov/pubmed/25368191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410533111
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