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Microtubules stabilize cell polarity by localizing rear signals

Microtubules are known to play an important role in cell polarity; however, the mechanism remains unclear. Using cells migrating persistently on micropatterned strips, we found that depolymerization of microtubules caused cells to change from persistent to oscillatory migration. Mathematical modelin...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Zhang, Jian, Guo, Wei-Hui, Wang, Yu-Li
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246331/
https://ncbi.nlm.nih.gov/pubmed/25368191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410533111
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