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An Annular Lipid Belt Is Essential for Allosteric Coupling and Viral Inhibition of the Antigen Translocation Complex TAP (Transporter Associated with Antigen Processing)

The transporter associated with antigen processing (TAP) constitutes a focal element in the adaptive immune response against infected or malignantly transformed cells. TAP shuttles proteasomal degradation products into the lumen of the endoplasmic reticulum for loading of major histocompatibility co...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Eggensperger, Sabine, Fisette, Olivier, Parcej, David, Schäfer, Lars V., Tampé, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246070/
https://ncbi.nlm.nih.gov/pubmed/25305015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.592832
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