Agelasine D Suppresses RANKL-Induced Osteoclastogenesis via Down-Regulation of c-Fos, NFATc1 and NF-κB

In the present study, we investigated the effect of agelasine D (AD) on osteoclastogenesis. Treatment of bone marrow macrophages (BMMs) with receptor activator of nuclear factor κB ligand (RANKL) resulted in a differentiation of BMMs into osteoclasts as evidenced by generation of tartrate-resistant...

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Bibliographic Details
Published in:Mar Drugs
Main Authors: Kang, Moo Rim, Jo, Sun Ah, Yoon, Yeo Dae, Park, Ki Hwan, Oh, Soo Jin, Yun, Jieun, Lee, Chang Woo, Nam, Ki-Hoan, Kim, Youngsoo, Han, Sang-Bae, Yu, Jiyeon, Rho, Jaerang, Kang, Jong Soon
Format: Artigo
Language:Inglês
Published: MDPI 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245549/
https://ncbi.nlm.nih.gov/pubmed/25421321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12115643
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