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Agelasine D Suppresses RANKL-Induced Osteoclastogenesis via Down-Regulation of c-Fos, NFATc1 and NF-κB
In the present study, we investigated the effect of agelasine D (AD) on osteoclastogenesis. Treatment of bone marrow macrophages (BMMs) with receptor activator of nuclear factor κB ligand (RANKL) resulted in a differentiation of BMMs into osteoclasts as evidenced by generation of tartrate-resistant...
Shranjeno v:
izdano v: | Mar Drugs |
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Main Authors: | , , , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
MDPI
2014
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4245549/ https://ncbi.nlm.nih.gov/pubmed/25421321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12115643 |
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