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Identification of a major I-Ek-restricted determinant of hen egg lysozyme: limitations of lymph node proliferation studies in defining immunodominance and crypticity.

We have chemically analyzed the peptides presented by I-Ek molecules after processing of hen egg lysozyme (HEL) by a murine B-lymphoma line or by splenocytes. In both cases, the identified peptides were derived from a single region of HEL, containing the core residues 85-96 with heterogeneous N and...

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Detalhes bibliográficos
Main Authors: Viner, N J, Nelson, C A, Unanue, E R
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC42454/
https://ncbi.nlm.nih.gov/pubmed/7534415
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