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An Improved Surface Passivation Method for Single-Molecule Studies

We herein report a surface passivation method for in vitro single-molecule studies, which more efficiently prevents non-specific binding of biomolecules as compared to the polyethylene glycol surface. The new surface does not perturb the behavior and activities of tethered biomolecules. It can also...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Hua, Boyang, Young Han, Kyu, Zhou, Ruobo, Kim, Hajin, Shi, Xinghua, Abeysirigunawardena, Sanjaya C., Jain, Ankur, Singh, Digvijay, Aggarwal, Vasudha, Woodson, Sarah A., Ha, Taekjip
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245390/
https://ncbi.nlm.nih.gov/pubmed/25306544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3143
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