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A 3D Time-Shared NOESY Experiment Designed to Provide Optimal Resolution for Accurate Assignment of NMR Distance Restraints in Large Proteins
Structure determination of proteins by solution NMR has become an established method, but challenges increase steeply with the size of proteins. Notably spectral crowding and signal overlap impair the analysis of cross-peaks in NOESY spectra that provide distance restraints for structural models. An...
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| Vydáno v: | J Biomol NMR |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4245328/ https://ncbi.nlm.nih.gov/pubmed/25381567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-014-9873-8 |
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