IgG Antibodies to Cyclic Citrullinated Peptides Exhibit Profiles Specific in Terms of IgG Subclasses, Fc-Glycans and a Fab-Peptide Sequence

The Fc-glycan profile of IgG(1) anti-citrullinated peptide antibodies (ACPA) in rheumatoid arthritis (RA) patients has recently been reported to be different from non-ACPA IgG(1), a phenomenon which likely plays a role in RA pathogenesis. Herein we investigate the Fc-glycosylation pattern of all ACP...

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Pubblicato in:PLoS One
Autori principali: Lundström, Susanna L., Fernandes-Cerqueira, Cátia, Ytterberg, A. Jimmy, Ossipova, Elena, Hensvold, Aase H., Jakobsson, Per-Johan, Malmström, Vivianne, Catrina, Anca I., Klareskog, Lars, Lundberg, Karin, Zubarev, Roman A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245247/
https://ncbi.nlm.nih.gov/pubmed/25426976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113924
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