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Advancements in the Development of HIF-1α-Activated Protein Switches for Use in Enzyme Prodrug Therapy
While gene-directed enzyme prodrug therapy has shown potential as a cancer therapeutic in animal and clinical trials, concerns over the efficacy, selectivity, and safety of gene delivery vehicles have restricted its advance. In an attempt to relieve some of the demands on targeted gene delivery vehi...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4245239/ https://ncbi.nlm.nih.gov/pubmed/25426963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114032 |
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