Circulating Programmed Death-1 as a Marker for Sustained High Hepatitis B Viral Load and Risk of Hepatocellular Carcinoma

OBJECTIVE: Recent evidence indicates a crucial role of the immunoinhibitory receptor programmed death-1 (PD-1) in enforcing T-cell dysfunction during chronic viral infection and cancer. We assessed the impact of circulating soluble PD-1 (sPD-1) levels on long-term dynamics of hepatitis B virus (HBV)...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cheng, Hsiang-Yun, Kang, Pei-Jen, Chuang, Ya-Hui, Wang, Ya-Hui, Jan, Meng-Chin, Wu, Chih-Feng, Lin, Chih-Lin, Liu, Chun-Jen, Liaw, Yun-Fan, Lin, Shi-Ming, Chen, Pei-Jer, Lee, Shou-Dong, Yu, Ming-Whei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245192/
https://ncbi.nlm.nih.gov/pubmed/25427199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095870
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