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Uncovering Caffeine’s Adenosine A(2A) Receptor Inverse Agonism in Experimental Parkinsonism

[Image: see text] Caffeine, the most consumed psychoactive substance worldwide, may have beneficial effects on Parkinson’s disease (PD) therapy. The mechanism by which caffeine contributes to its antiparkinsonian effects by acting as either an adenosine A(2A) receptor (A(2A)R) neutral antagonist or...

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Dettagli Bibliografici
Pubblicato in:ACS Chem Biol
Autori principali: Fernández-Dueñas, Víctor, Gómez-Soler, Maricel, López-Cano, Marc, Taura, Jaume J., Ledent, Catherine, Watanabe, Masahiko, Jacobson, Kenneth A., Vilardaga, Jean-Pierre, Ciruela, Francisco
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245165/
https://ncbi.nlm.nih.gov/pubmed/25268872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5005383
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