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Identification of 3-methylglutarylcarnitine. A new diagnostic metabolite of 3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency.

Deficiency of 3-hydroxy-3-methylglutaryl-coenzyme A (CoA) lyase affects the metabolism of leucine as well as ketogenesis. This disorder is one of an increasing list of inborn errors of metabolism that presents clinically like Reye's Syndrome or nonketotic hypoglycemia. Four patients with proven...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Roe, C R, Millington, D S, Maltby, D A
Format: Artigo
Langue:Inglês
Publié: 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC424505/
https://ncbi.nlm.nih.gov/pubmed/3958190
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