Role of sinoatrial node architecture in maintaining a balanced source-sink relationship and synchronous cardiac pacemaking

Normal heart rhythm (sinus rhythm) depends on regular activity of the sinoatrial node (SAN), a heterogeneous collection of specialized myocytes in the right atrium. SAN cells, in general, possess a unique electrophysiological profile that promotes spontaneous electrical activity (automaticity). Howe...

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Udgivet i:Front Physiol
Main Authors: Unudurthi, Sathya D., Wolf, Roseanne M., Hund, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244803/
https://ncbi.nlm.nih.gov/pubmed/25505419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00446
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