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Specificity and Autoregulation of Notch Binding by Tandem WW Domains in Suppressor of Deltex

WW domains target proline-tyrosine (PY) motifs and frequently function as tandem pairs. When studied in isolation, single WW domains are notably promiscuous and regulatory mechanisms are undoubtedly required to ensure selective interactions. Here, we show that the fourth WW domain (WW4) of Suppresso...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Jennings, Martin D., Blankley, Richard T., Baron, Martin, Golovanov, Alexander P., Avis, Johanna M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244684/
https://ncbi.nlm.nih.gov/pubmed/17656366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M703453200
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