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Specificity and Autoregulation of Notch Binding by Tandem WW Domains in Suppressor of Deltex
WW domains target proline-tyrosine (PY) motifs and frequently function as tandem pairs. When studied in isolation, single WW domains are notably promiscuous and regulatory mechanisms are undoubtedly required to ensure selective interactions. Here, we show that the fourth WW domain (WW4) of Suppresso...
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Published in: | J Biol Chem |
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Main Authors: | , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
2007
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244684/ https://ncbi.nlm.nih.gov/pubmed/17656366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M703453200 |
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