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Specificity and Autoregulation of Notch Binding by Tandem WW Domains in Suppressor of Deltex

WW domains target proline-tyrosine (PY) motifs and frequently function as tandem pairs. When studied in isolation, single WW domains are notably promiscuous and regulatory mechanisms are undoubtedly required to ensure selective interactions. Here, we show that the fourth WW domain (WW4) of Suppresso...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Jennings, Martin D., Blankley, Richard T., Baron, Martin, Golovanov, Alexander P., Avis, Johanna M.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244684/
https://ncbi.nlm.nih.gov/pubmed/17656366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M703453200
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