Propofol pretreatment attenuates lipopolysaccharide-induced acute lung injury in rats by activating the phosphoinositide-3-kinase/Akt pathway

The aim of this study was to investigate the effect of propofol pretreatment on lipopolysaccharide (LPS)-induced acute lung injury (ALI) and the role of the phosphoinositide-3-kinase/protein kinase B (PI3K/Akt) pathway in this procedure. Survival was determined 48 h after LPS injection. At 1 h after...

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Detalhes bibliográficos
Publicado no:Braz J Med Biol Res
Main Authors: Zhao, L.L., Hu, G.C., Zhu, S.S., Li, J.F., Liu, G.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Associação Brasileira de Divulgação Científica 2014
Assuntos:
Biomedical Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244672/
https://ncbi.nlm.nih.gov/pubmed/25387673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20143949
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