Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase.

The neutrophil has been implicated as an important mediator of vascular injury, especially after endotoxemia. This study examines neutrophil-mediated injury to human microvascular endothelial cells in vitro. We found that neutrophils stimulated by formyl-methionyl-leucyl-phenylalanine (FMLP), the co...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Smedly, L A, Tonnesen, M G, Sandhaus, R A, Haslett, C, Guthrie, L A, Johnston, R B, Henson, P M, Worthen, G S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424465/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3485659/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112426
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