Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase.

The neutrophil has been implicated as an important mediator of vascular injury, especially after endotoxemia. This study examines neutrophil-mediated injury to human microvascular endothelial cells in vitro. We found that neutrophils stimulated by formyl-methionyl-leucyl-phenylalanine (FMLP), the co...

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Hauptverfasser: Smedly, L A, Tonnesen, M G, Sandhaus, R A, Haslett, C, Guthrie, L A, Johnston, R B, Henson, P M, Worthen, G S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC424465/
https://ncbi.nlm.nih.gov/pubmed/3485659
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