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Effects of histone deacetylase inhibitor valproic acid on skeletal myocyte development
The tight interaction between genomic DNA and histones, which normally represses gene transcription, can be relaxed by histone acetylation. This loosening of the DNA-histone complex is important for selective gene activation during stem cell differentiation. Histone acetylation may be increased thro...
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| Published in: | Sci Rep |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244627/ https://ncbi.nlm.nih.gov/pubmed/25423891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07207 |
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