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Effects of the histone deacetylase inhibitor valproic acid on Notch signalling in human neuroblastoma cells

Neuroblastoma (NB), a sympathetically derived childhood tumour, shows characteristics of neuronal precursor cells, suggesting a halted differentiation process. We have previously shown that the Notch signalling cascade, a key player during normal neurogenesis, also might be involved in NB differenti...

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Detalhes bibliográficos
Main Authors: Stockhausen, M-T, Sjölund, J, Manetopoulos, C, Axelson, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361888/
https://ncbi.nlm.nih.gov/pubmed/15685243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602309
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