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In Silico Screening for Inhibitors of P-Glycoprotein That Target the Nucleotide Binding Domains
Multidrug resistances and the failure of chemotherapies are often caused by the expression or overexpression of ATP-binding cassette transporter proteins such as the multidrug resistance protein, P-glycoprotein (P-gp). P-gp is expressed in the plasma membrane of many cell types and protects cells fr...
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| Publicat a: | Mol Pharmacol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244591/ https://ncbi.nlm.nih.gov/pubmed/25270578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.095414 |
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