Atomoxetine Prevents Dexamethasone-Induced Skeletal Muscle Atrophy in Mice

Skeletal muscle atrophy remains a clinical problem in numerous pathologic conditions. β(2)-Adrenergic receptor agonists, such as formoterol, can induce mitochondrial biogenesis (MB) to prevent such atrophy. Additionally, atomoxetine, an FDA-approved norepinephrine reuptake inhibitor, was positive in...

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Detalles Bibliográficos
Publicado en:J Pharmacol Exp Ther
Autores principales: Jesinkey, Sean R., Korrapati, Midhun C., Rasbach, Kyle A., Beeson, Craig C., Schnellmann, Rick G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2014
Materias:
Drug Discovery and Translational Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244586/
https://ncbi.nlm.nih.gov/pubmed/25292181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.217380
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