Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration

Pharmacologic agents to enhance liver regeneration after injury would have wide therapeutic application. Based on previous work suggesting inhibition of bone morphogenetic protein (BMP) signaling stimulates liver regeneration, we tested known and novel BMP inhibitors for their ability to accelerate...

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Bibliografiske detaljer
Udgivet i:J Pharmacol Exp Ther
Main Authors: Tsugawa, Daisuke, Oya, Yuki, Masuzaki, Ryota, Ray, Kevin, Engers, Darren W., Dib, Martin, Do, Nhue, Kuramitsu, Kaori, Ho, Karen, Frist, Audrey, Yu, Paul B., Bloch, Kenneth D., Lindsley, Craig W., Hopkins, Corey R., Hong, Charles C., Karp, Seth J.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2014
Fag:
Gastrointestinal, Hepatic, Pulmonary, and Renal
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244585/
https://ncbi.nlm.nih.gov/pubmed/25271257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.216903
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