Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration

Pharmacologic agents to enhance liver regeneration after injury would have wide therapeutic application. Based on previous work suggesting inhibition of bone morphogenetic protein (BMP) signaling stimulates liver regeneration, we tested known and novel BMP inhibitors for their ability to accelerate...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Tsugawa, Daisuke, Oya, Yuki, Masuzaki, Ryota, Ray, Kevin, Engers, Darren W., Dib, Martin, Do, Nhue, Kuramitsu, Kaori, Ho, Karen, Frist, Audrey, Yu, Paul B., Bloch, Kenneth D., Lindsley, Craig W., Hopkins, Corey R., Hong, Charles C., Karp, Seth J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Gastrointestinal, Hepatic, Pulmonary, and Renal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244585/
https://ncbi.nlm.nih.gov/pubmed/25271257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.216903
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