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RNA Polymerase II Transcription: Structure and Mechanism

A minimal RNA polymerase II (pol II) transcription system comprises the polymerase and five general transcription factors (GTFs) TFIIB, -D, -E, -F, and -H. The addition of Mediator enables a response to regulatory factors. The GTFs are required for promoter recognition and the initiation of transcri...

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Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: Liu, Xin, Bushnell, David A., Kornberg, Roger D.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244541/
https://ncbi.nlm.nih.gov/pubmed/23000482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2012.09.003
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