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RTCB-1 Mediates Neuroprotection via XBP-1 mRNA Splicing in the Unfolded Protein Response Pathway

Parkinson's disease (PD), the second most prevalent neurodegenerative disorder, is characterized by the degeneration of dopamine (DA) neurons and age-dependent formation of protein inclusions that contain the α-synuclein (α-syn) protein. RNA interference (RNAi) screening using Caenorhabditis el...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Ray, Arpita, Zhang, Siyuan, Rentas, Courtney, Caldwell, Kim A., Caldwell, Guy A.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244473/
https://ncbi.nlm.nih.gov/pubmed/25429148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1945-14.2014
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