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Cytoskeletal confinement of CX(3)CL1 limits its susceptibility to proteolytic cleavage by ADAM10
CX(3)CL1 is a unique chemokine that acts both as a transmembrane endothelial adhesion molecule and, upon proteolytic cleavage, a soluble chemoattractant for circulating leukocytes. The constitutive release of soluble CX(3)CL1 requires the interaction of its transmembrane species with the integral me...
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| Опубликовано в: : | Mol Biol Cell |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Cell Biology
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244198/ https://ncbi.nlm.nih.gov/pubmed/25253723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-11-0633 |
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