Загрузка...

Cytoskeletal confinement of CX(3)CL1 limits its susceptibility to proteolytic cleavage by ADAM10

CX(3)CL1 is a unique chemokine that acts both as a transmembrane endothelial adhesion molecule and, upon proteolytic cleavage, a soluble chemoattractant for circulating leukocytes. The constitutive release of soluble CX(3)CL1 requires the interaction of its transmembrane species with the integral me...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Mol Biol Cell
Главные авторы: Wong, Harikesh S., Jaumouillé, Valentin, Heit, Bryan, Doodnauth, Sasha A., Patel, Sajedabanu, Huang, Yi-Wei, Grinstein, Sergio, Robinson, Lisa A.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244198/
https://ncbi.nlm.nih.gov/pubmed/25253723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-11-0633
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!