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Proteolytic cleavage of amyloid precursor protein by ADAM10 mediates proliferation and migration in breast cancer

BACKGROUND: Amyloid precursor protein (APP), best known for its association with Alzheimer disease, has recently been implicated in breast cancer progression. However, the precise mechanism involved remains unclear. Here, we investigated the role of APP proteolytic cleavage in breast cancer function...

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Bibliografski detalji
Izdano u:EBioMedicine
Glavni autori: Tsang, Julia Y.S., Lee, Michelle A., Chan, Tsz-Hei, Li, Joshua, Ni, Yun-Bi, Shao, Yan, Chan, Siu-Ki, Cheungc, Sai-Yin, Lau, Kwok-Fai, Tse, Gary M.K.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306343/
https://ncbi.nlm.nih.gov/pubmed/30470613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.11.012
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