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Inhibition of JNK Aggravates the Recovery of Rat Hearts after Global Ischemia: The Role of Mitochondrial JNK

c-Jun N-terminal kinase (JNK), a stress-activated MAPK, is activated during cardiac ischemia-reperfusion (IR). The role of JNK inhibitors in cardioprotection against IR still remains controversial, in part, due to spill-over effects of non-specific inhibitors. In the present study, we sought to exam...

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Vydáno v:PLoS One
Hlavní autoři: Jang, Sehwan, Javadov, Sabzali
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244102/
https://ncbi.nlm.nih.gov/pubmed/25423094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113526
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