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Ectodomain shedding of the glycoprotein GP of Ebola virus

In this study, release of abundant amounts of the Ebola virus (EBOV) surface glycoprotein GP in a soluble form from virus-infected cells was investigated. We demonstrate that the mechanism responsible for the release of GP is ectodomain shedding mediated by cellular sheddases. Proteolytic cleavage t...

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Bibliographic Details
Main Authors: Dolnik, Olga, Volchkova, Valentina, Garten, Wolfgang, Carbonnelle, Caroline, Becker, Stephan, Kahnt, Jörg, Ströher, Ute, Klenk, Hans-Dieter, Volchkov, Viktor
Format: Artigo
Language:Inglês
Published: 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC424403/
https://ncbi.nlm.nih.gov/pubmed/15103332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600219
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