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Ectodomain shedding of the glycoprotein GP of Ebola virus

In this study, release of abundant amounts of the Ebola virus (EBOV) surface glycoprotein GP in a soluble form from virus-infected cells was investigated. We demonstrate that the mechanism responsible for the release of GP is ectodomain shedding mediated by cellular sheddases. Proteolytic cleavage t...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Dolnik, Olga, Volchkova, Valentina, Garten, Wolfgang, Carbonnelle, Caroline, Becker, Stephan, Kahnt, Jörg, Ströher, Ute, Klenk, Hans-Dieter, Volchkov, Viktor
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2004
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424403/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15103332/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600219
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