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An osmolyte mitigates the destabilizing effect of protein crowding

Most theories predict that macromolecular crowding stabilizes globular proteins, but recent studies show that weak attractive interactions can result in crowding-induced destabilization. Osmolytes are ubiquitous in biology and help protect cells against stress. Given that dehydration stress adds to...

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Bibliografiska uppgifter
I publikationen:Protein Sci
Huvudupphovsmän: Sarkar, Mohona, Pielak, Gary J
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243990/
https://ncbi.nlm.nih.gov/pubmed/24963990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2510
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