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An osmolyte mitigates the destabilizing effect of protein crowding
Most theories predict that macromolecular crowding stabilizes globular proteins, but recent studies show that weak attractive interactions can result in crowding-induced destabilization. Osmolytes are ubiquitous in biology and help protect cells against stress. Given that dehydration stress adds to...
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| 出版年: | Protein Sci |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Publishing Ltd
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4243990/ https://ncbi.nlm.nih.gov/pubmed/24963990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2510 |
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