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Differences in the rate of oestrogen-induced apoptosis in breast cancer by oestradiol and the triphenylethylene bisphenol

BACKGROUND AND PURPOSE: Triphenylethylene (TPE)-like compounds were the first agents to be used in the treatment of metastatic breast cancer in postmenopausal women. Although structurally related to the anti-oestrogen, 4-hydroxytamoxifen, TPEs possess oestrogenic properties in fully oestrogenized br...

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Pubblicato in:Br J Pharmacol
Autori principali: Obiorah, I E, Jordan, V C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243979/
https://ncbi.nlm.nih.gov/pubmed/24819221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12762
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