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Palmitoylethanolamide normalizes intestinal motility in a model of post-inflammatory accelerated transit: involvement of CB(1) receptors and TRPV1 channels

BACKGROUND AND PURPOSE: Palmitoylethanolamide (PEA), a naturally occurring acylethanolamide chemically related to the endocannabinoid anandamide, interacts with targets that have been identified in peripheral nerves controlling gastrointestinal motility, such as cannabinoid CB(1) and CB(2) receptors...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Capasso, Raffaele, Orlando, Pierangelo, Pagano, Ester, Aveta, Teresa, Buono, Lorena, Borrelli, Francesca, Di Marzo, Vincenzo, Izzo, Angelo A
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243976/
https://ncbi.nlm.nih.gov/pubmed/24818658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12759
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