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Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables (Brassicaceae): evidence for TRPA1-independent effects

BACKGROUND AND PURPOSE: Allyl isothiocyanate (AITC, mustard oil), a constituent of many common cruciferous vegetables (Brassicaceae), activates transient receptor potential of ankyrin type-1 (TRPA1) channels, claimed to regulate gastrointestinal contractility. In this study, we have investigated the...

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Main Authors: Capasso, Raffaele, Aviello, Gabriella, Romano, Barbara, Borrelli, Francesca, De Petrocellis, Luciano, Di Marzo, Vincenzo, Izzo, Angelo A
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372844/
https://ncbi.nlm.nih.gov/pubmed/21955242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01703.x
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