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Hormone Therapy plus mTOR Inhibitors in the Treatment of Endometrial Carcinoma
Hormonal therapies such as progestins have only modest activity in the treatment of advanced endometrial cancer. Mechanisms of resistance to progestin therapy are not well understood. However, activation of the PI3K/AKT/mTOR pathway has been associated with resistance to hormonal therapy and alterat...
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| Опубликовано в: : | Oncol Hematol Rev |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4243922/ https://ncbi.nlm.nih.gov/pubmed/25431800 |
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