Population pharmacokinetic–pharmacodynamic modelling of mycophenolic acid in paediatric renal transplant recipients in the early post-transplant period

AIM: The purpose of this study was to develop a population pharmacokinetic and pharmacodynamic (PK−PD) model for mycophenolic acid (MPA) in paediatric renal transplant recipients in the early post-transplant period. METHODS: A total of 214 MPA plasma concentrations−time data points from 24 patients...

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Veröffentlicht in:Br J Clin Pharmacol
Hauptverfasser: Dong, Min, Fukuda, Tsuyoshi, Cox, Shareen, de Vries, Marij T, Hooper, David K, Goebel, Jens, Vinks, Alexander A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Paediatric Clinical Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243885/
https://ncbi.nlm.nih.gov/pubmed/24837828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12426
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