Heart ischaemia–reperfusion induces local up-regulation of vasoconstrictor endothelin ETB receptors in rat coronary arteries downstream of occlusion

BACKGROUND AND PURPOSE: Endothelins act via two receptor subtypes, ET(A) and ET(B). Under physiological conditions in coronary arteries, ET(A) receptors expressed in smooth muscle cells mediate vasoconstriction whereas ET(B) receptors mainly found in endothelial cells mediate vasorelaxation. However...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Skovsted, G F, Kruse, L S, Larsen, R, Pedersen, A F, Trautner, S, Sheykhzade, M, Edvinsson, L
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243850/
https://ncbi.nlm.nih.gov/pubmed/24467585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12606
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