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Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ET(B) receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat
BACKGROUND: Coronary artery remodelling and vasospasm is a complication of acute myocardial ischemia and reperfusion. The underlying mechanisms are complex, but the vasoconstrictor peptide endothelin-1 is suggested to have an important role. This study aimed to determine whether the expression of en...
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| Izdano u: | PLoS One |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5360328/ https://ncbi.nlm.nih.gov/pubmed/28323857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174119 |
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