CD39 Modulates Hematopoietic Stem Cell Recruitment and Promotes Liver Regeneration in Mice and Humans After Partial Hepatectomy

OBJECTIVE: To study molecular mechanisms involved in hematopoietic stem cell (HSC) mobilization after liver resection and determine impacts on liver regeneration. BACKGROUND: Extracellular nucleotide-mediated cell signaling has been shown to boost liver regeneration. Ectonucleotidases of the CD39 fa...

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Udgivet i:Ann Surg
Main Authors: Schmelzle, Moritz, Duhme, Constanze, Junger, Wolfgang, Salhanick, Steven D., Chen, Yu, Wu, Yan, Toxavidis, Vasilis, Csizmadia, Eva, Han, Lihui, Bian, Shu, Fürst, Günter, Nowak, Martina, Karp, Seth J., Knoefel, Wolfram T., Esch, Jan Schulte am, Robson, Simon C.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243517/
https://ncbi.nlm.nih.gov/pubmed/23474584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0b013e31826c3ec2
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