Loss of high affinity cardiac beta adrenergic receptors in dogs with heart failure.

We studied the alterations in myocardial beta-adrenergic receptor-adenylate cyclase activity and muscarinic receptor density in a canine model of left ventricular (LV) failure. LV failure was characterized by a doubling of LV weight/body weight ratio (3.3 +/- 0.1 to 6.9 +/- 0.4 g/kg) and an elevatio...

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Publicado en:	J Clin Invest
Autores principales:	Vatner, D E, Vatner, S F, Fujii, A M, Homcy, C J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1985
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424349/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3001147/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112235
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