Role of intact cardiac nerves and reflex mechanisms in desensitization to catecholamines in conscious dogs.

To study chronic catecholamine desensitization, mini-osmotic pumps were implanted subcutaneously to deliver NE, (0.5 micrograms/kg/min) or saline over 3-4 wk in dogs instrumented with left ventricular (LV) pressure gauges and arterial and left atrial pressure catheters. An acute challenge to NE (0.4...

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Publié dans:	J Clin Invest
Auteurs principaux:	Nejima, J, Uemura, N, Vatner, D E, Homcy, C J, Hintze, T H, Vatner, S F
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329843/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2254459/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114941
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