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Genomic mapping of the MHC transactivator CIITA using an integrated ChIP-seq and genetical genomics approach
BACKGROUND: The master transactivator CIITA is essential to the regulation of Major Histocompatibility Complex (MHC) class II genes and an effective immune response. CIITA is known to modulate a small number of non-MHC genes involved in antigen presentation such as CD74 and B2M but its broader genom...
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| 發表在: | Genome Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4243378/ https://ncbi.nlm.nih.gov/pubmed/25366989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0494-z |
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