Dynamic O-Linked N-Acetylglucosamine Modification of Proteins Affects Stress Responses and Survival of Mesothelial Cells Exposed to Peritoneal Dialysis Fluids

The ability of cells to respond and survive stressful conditions is determined, in part, by the attachment of O-linked N-acetylglucosamine (O-GlcNAc) to proteins (O-GlcNAcylation), a post-translational modification dependent on glucose and glutamine. This study investigates the role of dynamic O-Glc...

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Опубликовано в: :J Am Soc Nephrol
Главные авторы: Herzog, Rebecca, Bender, Thorsten O., Vychytil, Andreas, Bialas, Katarzyna, Aufricht, Christoph, Kratochwill, Klaus
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2014
Предметы:
Basic Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243353/
https://ncbi.nlm.nih.gov/pubmed/24854264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013101128
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