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Dynamic O-Linked N-Acetylglucosamine Modification of Proteins Affects Stress Responses and Survival of Mesothelial Cells Exposed to Peritoneal Dialysis Fluids

The ability of cells to respond and survive stressful conditions is determined, in part, by the attachment of O-linked N-acetylglucosamine (O-GlcNAc) to proteins (O-GlcNAcylation), a post-translational modification dependent on glucose and glutamine. This study investigates the role of dynamic O-Glc...

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Pubblicato in:J Am Soc Nephrol
Autori principali: Herzog, Rebecca, Bender, Thorsten O., Vychytil, Andreas, Bialas, Katarzyna, Aufricht, Christoph, Kratochwill, Klaus
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243353/
https://ncbi.nlm.nih.gov/pubmed/24854264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013101128
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