Renal Angiotensin-Converting Enzyme Is Essential for the Hypertension Induced by Nitric Oxide Synthesis Inhibition

The kidney is an important source of angiotensin-converting enzyme (ACE) in many species, including humans. However, the specific effects of local ACE on renal function and, by extension, BP control are not completely understood. We previously showed that mice lacking renal ACE, are resistant to the...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Giani, Jorge F., Janjulia, Tea, Kamat, Nikhil, Seth, Dale M., Blackwell, Wendell-Lamar B., Shah, Kandarp H., Shen, Xiao Z., Fuchs, Sebastien, Delpire, Eric, Toblli, Jorge E., Bernstein, Kenneth E., McDonough, Alicia A., Gonzalez-Villalobos, Romer A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2014
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243348/
https://ncbi.nlm.nih.gov/pubmed/25012170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013091030
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