A Modern Understanding of the Traditional and Nontraditional Biological Functions of Angiotensin-Converting Enzyme

Angiotensin-converting enzyme (ACE) is a zinc-dependent peptidase responsible for converting angiotensin I into the vasoconstrictor angiotensin II. However, ACE is a relatively nonspecific peptidase that is capable of cleaving a wide range of substrates. Because of this, ACE and its peptide substrat...

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Detalhes bibliográficos
Main Authors: Bernstein, Kenneth E., Ong, Frank S., Blackwell, Wendell-Lamar B., Shah, Kandarp H., Giani, Jorge F., Gonzalez-Villalobos, Romer A., Shen, Xiao Z., Fuchs, Sebastien
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Review Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565918/
https://ncbi.nlm.nih.gov/pubmed/23257181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.112.006809
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