Phase II Randomized, Placebo-controlled Trial of Green Tea Extract in Patients with High-risk Oral Premalignant Lesions

Epidemiologic and preclinical data support the oral-cancer prevention potential of green tea extract (GTE). We randomly assigned patients with high-risk oral premalignant lesions (OPLs) to receive GTE at 500 mg/m(2), 750 mg/m(2), or 1000 mg/m(2) or placebo TID for 12 weeks, evaluating biomarkers in...

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Gepubliceerd in:Cancer Prev Res (Phila)
Hoofdauteurs: Tsao, Anne S., Liu, Diane, Martin, Jack, Tang, Xi-ming, Lee, J. Jack, El-Naggar, Adel K., Wistuba, Ignacio, Culotta, Kirk S., Mao, Li, Gillenwater, Ann, Sagesaka, Yuko M., Hong, Waun K., Papadimitrakopoulou, Vassiliki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243312/
https://ncbi.nlm.nih.gov/pubmed/19892663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-09-0121
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